After making their way through high school (twice), big changes are in store for officers Schmidt and Jenko when they go deep undercover at a local college. But when Jenko meets a kindred spirit on the football team, and Schmidt infiltrates the bohemian art major scene, they begin to question their partnership. Now they don't have to just crack the case - they have to figure out if they can have a mature relationship. If these two overgrown adolescents can grow from freshmen into real men, college might be the best thing that ever happened to them.

In high school, Schmidt was a dork and Jenko was the popular jock. After graduation, both of them joined the police force and ended up as partners riding bicycles in the city park. Since they are young and look like high school students, they are assigned to an undercover unit to infiltrate a drug ring that is supplying high school students synthetic drugs.