When a woman trying to outrun her past ends up trapped between a zombie outbreak and warring militia groups, she must fight to find her way back home.

An ex-Navy seal (Mehcad Brooks), his girlfriend (Serinda Swan) and their friends head out on a road trip to New Orleans. The group decides to stop at a roadside convenience store owned by Chopper (Sid Haig), who tells them the tale of Lockjaw, a fabled god-like creature who is half-man, half-alligator.